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Can your body make antibodies for pathogens that have never been in contact with?

Can your body make antibodies for pathogens that have never been in contact with? Why or why not?

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When the sick human begins the internal fight against the external organisms that produce the disease, the immune system starts up and secretes the specific antibodies to fight and eliminate the bacteria, parasites or viruses that cause the discomfort.

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When the sick human begins the internal fight against the external organisms that produce the disease, the immune system starts up and secretes the specific antibodies to fight and eliminate the bacteria, parasites or viruses that cause the discomfort.